Basic Information

Symbol
SNX1
RNA class
mRNA
Alias
Sorting Nexin 1 HsT17379 Vps5 Sorting Nexin-1 MGC8664 SNX1A Sorting Nexin 1A
Location (GRCh38)
15:64094123-64146090
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_003099.5
Sequence length
8214.0 nt
GC content
0.4498

Transcripts

ID Sequence Length GC content
NM_001242933.2 NCBI
GUUGUUGCGGCUUCCGCCGCGGGUGGAAGAAGAUGGCGUCGGGUGGUGG… 7740 nt 0.4513
NM_003099.5 NCBI
GUUGUUGCGGCUUCCGCCGCGGGUGGAAGAAGAUGGCGUCGGGUGGUGG… 8214 nt 0.4498
NM_148955.4 NCBI
GUUGUUGCGGCUUCCGCCGCGGGUGGAAGAAGAUGGCGUCGGGUGGUGG… 8019 nt 0.4498
Summary

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Forensic Context

No relevant information is available at the moment.