Basic Information
MANE select
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| GCACUCUCGGGAUGGAGGGCGAGCGCCGGGCAUCGCAGGCGCCCUCCUC… | 1856 nt | 0.4122 | |
| GCACUCUCGGGAUGGAGGGCGAGCGCCGGGCAUCGCAGGCGCCCUCCUC… | 1736 nt | 0.4119 | |
| GCACUCUCGGGAUGGAGGGCGAGCGCCGGGCAUCGCAGGCGCCCUCCUC… | 1571 nt | 0.4169 |
Summary
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region like some family members, and its exact function is unknown. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Jun 2010]
Forensic Context
A study in humans demonstrated that the SNX7 was upregulated during long-term weight loss (0 to 12 months) in weight losers within subcutaneous adipose tissue [Bollepalli et al. DOI:10.1038/ijo.2017.245].