Basic Information

Symbol
SPRR1B
RNA class
mRNA
Alias
Small Proline Rich Protein 1B Cornifin-B GADD33 Small Proline-Rich Protein IB 14.9 KDa Pancornulin SPR-IB SPRR1 Small Proline-Rich Protein 1B CORNIFIN
Location (GRCh38)
1:153031203-153032900
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_003125.3
Sequence length
619.0 nt
GC content
0.5267

Transcripts

ID Sequence Length GC content
NM_003125.3 NCBI
ACCAGUUCUAAGGGACCAUACAGAGUAUUCCUCUCUUCACACCAGGACC… 619 nt 0.5267
Summary

The protein encoded by this gene is an envelope protein of keratinocytes. The encoded protein is crosslinked to membrane proteins by transglutaminase, forming an insoluble layer under the plasma membrane. This protein is proline-rich and contains several tandem amino acid repeats. [provided by RefSeq, Nov 2015]

Forensic Context

The literature review identifies the SPRR1B as a protein marker found in vaginal fluid for body fluid identification [Alex et al. DOI:10.1016/j.scijus.2025.101320].