Basic Information

Symbol
SQOR
RNA class
mRNA
Alias
Sulfide Quinone Oxidoreductase CGI-44 SQRDL SQR Sulfide:Quinone Oxidoreductase, Mitochondrial Sulfide Quinone Reductase-Like (Yeast) Sulfide Quinone Reductase-Like Sulfide Dehydrogenase Like Sulfide Dehydrogenase-Like EC 1.8.5.8 PRO1975
Location (GRCh38)
15:45631148-45691299
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_021199.4
Sequence length
1701.0 nt
GC content
0.4921

Transcripts

ID Sequence Length GC content
NM_001271213.2 NCBI
CUCAUUUUCUCUUGCCGCCACCAUGUAAGAAGCGCCUUUCGCCUCCCUC… 1797 nt 0.4886
NM_021199.4 NCBI
AGUCCAGGCCUUGAGACCCAGAAGGGAGCGAAGGUUUUUGCUGCGCCAA… 1701 nt 0.4921
Summary

The protein encoded by this gene may function in mitochondria to catalyze the conversion of sulfide to persulfides, thereby decreasing toxic concencrations of sulfide. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2012]

Forensic Context

A study in humans demonstrated that the SQOR gene, involved in amino acid metabolism, was upregulated as part of the metabolism of amino acids and derivatives pathway in the colon and heart of sepsis patients compared to uninfected controls [Pinheiro da Silva et al. DOI:10.1111/jcmm.17938].