This gene encodes a protein kinase similar to a protein kinase which is specific for the SR (serine/arginine-rich domain) family of splicing factors. A highly similar protein has been shown to play a role in muscle development in mice. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Forensic Context
A study in mice selectively bred for high or low methamphetamine consumption identified the SRPK3 as a network hub node among ventral midbrain differentially expressed genes overexpressed in the low-drinking line, where it exhibited connectivity differing by at least 0.5 and was a hub in the green coexpression module [Hitzemann et al. DOI:10.3390/brainsci9070155].