Basic Information

Symbol
ST18
RNA class
mRNA
Alias
ST18 C2H2C-Type Zinc Finger Transcription Factor Zinc Finger Protein 387 KIAA0535 ZC2HC10 ZC2H2C3 ZNF387 NZF-3 NZF3 Suppression Of Tumorigenicity 18 (Breast Carcinoma) (Zinc Finger Protein) Suppression Of Tumorigenicity 18, Zinc Finger Neural Zinc Finger Transcription Factor 3 Suppression Of Tumorigenicity 18 Protein ST18, C2H2C-Type Zinc Finger
Location (GRCh38)
Forensic tag(s)
Forensic psychiatry evaluation

MANE select

Transcript ID
NM_001352837.2
Sequence length
6302.0 nt
GC content
0.4107

Transcripts

ID Sequence Length GC content
GAUUCUAUGGAACCUUUUUGUAGGGAGAAGGGCAGGAUGUUUUUAACUG… 5130 nt 0.4041
GAUUCUAUGGAACCUUUUUGUAGGGAGAAGGGCAGGAUGUUUUUAACUG… 6390 nt 0.4102
AUCACAGAGUGUCCCUGCACACCACACAACGACACAAACACUGGACUAA… 6232 nt 0.4119
CGCUUGUUCGCUCACUCUCAGUGAAAAGAGUUUUGAAAUGAGUUCUGAA… 2713 nt 0.3701
CGCUUGUUCGCUCACUCUCAGUGAAAAGAGUUUUGAAAUGAGUUCUGAA… 4559 nt 0.3806
CGCUUGUUCGCUCACUCUCAGUGAAAAGAGUUUUGAAAUGAGUUCUGAA… 4539 nt 0.3805
GAUUCUAUGGAACCUUUUUGUAGGGAGAAGGGCAGGAUGUUUUUAACUG… 4550 nt 0.3811
GAUUCUAUGGAACCUUUUUGUAGGGAGAAGGGCAGGAUGUUUUUAACUG… 2724 nt 0.3711
GAUUCUAUGGAACCUUUUUGUAGGGAGAAGGGCAGGAUGUUUUUAACUG… 6201 nt 0.4098
Showing 51 to 59 of 59 entries
Summary

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cytokine-mediated signaling pathway; negative regulation of cell population proliferation; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of protein-DNA complex. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in human samples using single-cell/nucleus RNA sequencing identified the ST18 as a marker for manual annotation of oligodendrocyte clusters in an Alzheimer's disease dataset [Xue et al. DOI:10.3233/JAD-230559].