Basic Information

Symbol
STK11
RNA class
mRNA
Alias
Serine/Threonine Kinase 11 LKB1 PJS Serine/Threonine-Protein Kinase STK11 Polarization-Related Protein LKB1 Renal Carcinoma Antigen NY-REN-19 Liver Kinase B1 EC 2.7.11.1 HLKB1 Serine/Threonine Kinase 11 (Peutz-Jeghers Syndrome) Serine/Threonine-Protein Kinase LKB1 Serine/Threonine-Protein Kinase 11
Location (GRCh38)
19:1177558-1228431
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_000455.5
Sequence length
3293.0 nt
GC content
0.6702

Transcripts

ID Sequence Length GC content
NM_000455.5 NCBI
GAGGUAAACAAGAUGGCGGCGGCGUGUCGGGCGCGGAAGGGGGAGGCGG… 3293 nt 0.6702
NM_001407255.1 NCBI
GAGGUAAACAAGAUGGCGGCGGCGUGUCGGGCGCGGAAGGGGGAGGCGG… 2482 nt 0.6700
Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cell polarity and energy metabolism and functions as a tumor suppressor. Mutations in this gene have been associated with the autosomal dominant Peutz-Jeghers syndrome, as well as with skin, pancreatic, and testicular cancers. [provided by RefSeq, May 2022] CIViC Summary for STK11 Gene

Forensic Context

No relevant information is available at the moment.