Basic Information

Symbol
STK17A
RNA class
mRNA
Alias
Serine/Threonine Kinase 17a DRAK1 DAP Kinase-Related Apoptosis-Inducing Protein Kinase 1 Serine/Threonine Kinase 17a (Apoptosis-Inducing) Death-Associated Protein Kinase-Related 1 Serine/Threonine-Protein Kinase 17A EC 2.7.11.1
Location (GRCh38)
7:43582758-43650713
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_004760.3
Sequence length
3918.0 nt
GC content
0.3925

Transcripts

ID Sequence Length GC content
NM_004760.3 NCBI
GCAGUCCGAGCGCCGCGCUGGGGAGAGCGGGUGUUUGAAGGCUCCGCGG… 3918 nt 0.3925
Summary

This gene is a member of the DAP kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase domain. The protein has apoptosis-inducing activity. [provided by RefSeq, Jul 2008]

Forensic Context

A study in human skin demonstrated that the STK17A is significantly up-regulated in thermally injured tissue during the early wound repair process [Greco et al. DOI:10.1016/j.burns.2009.06.211]. In rhesus macaques, transcriptomic analysis identified the STK17A as a differentially expressed gene that is upregulated in animals with hypertrophic cardiomyopathy [Rivas et al. DOI:10.1038/s41598-024-82770-4].