Basic Information

Symbol
STK40
RNA class
mRNA
Alias
Serine/Threonine Kinase 40 SgK495 SHIK SINK-Homologous Serine/Threonine-Protein Kinase SINK-Homologous Serine/Threonine Kinase Serine/Threonine-Protein Kinase 40 Sugen Kinase 495 EC 2.7.11.1 MGC4796 Ser/Thr-Like Kinase EC 2.7.11 SGK495
Location (GRCh38)
1:36339620-36385927
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001282547.2
Sequence length
3645.0 nt
GC content
0.5926

Transcripts

ID Sequence Length GC content
NM_001282546.2 NCBI
ACUUCCGUUGUCAGGUGGCGGCGCCGCAGCCAUGGAGGGAGGCGGCGGC… 3660 nt 0.5926
NM_001282547.2 NCBI
ACUUCCGUUGUCAGGUGGCGGCGCCGCAGCCAUGGAGGGAGGCGGCGGC… 3645 nt 0.5926
NM_032017.3 NCBI
ACUUCCGUUGUCAGGUGGCGGCGCCGCAGCCAUGGAGGGAGGCGGCGGC… 3882 nt 0.5884
Summary

Predicted to enable ATP binding activity; protein serine kinase activity; and protein serine/threonine kinase activity. Predicted to be involved in regulation of MAPK cascade. Predicted to act upstream of or within several processes, including glycogen metabolic process; lung development; and respiratory system process. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in human pediatric sepsis patients demonstrated that the STK40 exhibited increased polyadenylation in viral compared to bacterial infection samples, identifying it as a candidate gene for differential polyadenylation analysis between infection types [He et al. DOI:10.1186/s12879-025-11078-z].