Basic Information

Symbol
STMN3
RNA class
mRNA
Alias
Stathmin 3 SCLIP SCG10-Like Protein Stathmin-Like 3 Stathmin-3
Location (GRCh38)
20:63639705-63657682
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_015894.4
Sequence length
2248.0 nt
GC content
0.6308

Transcripts

ID Sequence Length GC content
NM_001276310.2 NCBI
ACACCGCUGCGGCCUCGGGGACCACCCUUUGCGACGCCCGCGCCACCUG… 2344 nt 0.6361
NM_015894.4 NCBI
ACUGCAGCACCAGCCGUCUGCAGCUCCGGCCGCCACUUGCGCCUCUCCA… 2248 nt 0.6308
Summary

This gene encodes a protein which is a member of the stathmin protein family. Members of this protein family form a complex with tubulins at a ratio of 2 tubulins for each stathmin protein. Microtubules require the ordered assembly of alpha- and beta-tubulins, and formation of a complex with stathmin disrupts microtubule formation and function. A pseudogene of this gene is located on chromosome 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Forensic Context

A study in rats demonstrated that the STMN3 was identified as a differentially expressed RNA marker in the hypothalamus during hypothermia, with its expression being significantly more abundant in control hypothalami (62 tags) compared to hypothermic hypothalami (20 tags) [Takamiya et al. DOI:10.1016/J.Jflm.2012.04.017].