Basic Information

Symbol
STT3B
RNA class
mRNA
Alias
STT3 Oligosaccharyltransferase Complex Catalytic Subunit B STT3-B SIMP Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit STT3B STT3B, Catalytic Subunit Of The Oligosaccharyltransferase Complex Dolichyl-Diphosphooligosaccharide Protein Glycotransferase Source Of Immunodominant MHC-Associated Peptides Homolog Oligosaccharyl Transferase Subunit STT3B FLJ90106 STT3, Subunit Of The Oligosaccharyltransferase Complex, Homolog B (S. Cerevisiae) STT3B, Subunit Of The Oligosaccharyltransferase Complex (Catalytic) STT3, Subunit Of The Oligosaccharyltransferase Complex, Homolog B Source Of Immunodominant MHC Associated Peptides Homolog Of Yeast STT3 EC 2.4.99.18 EC 2.4.1.119 CDG1X
Location (GRCh38)
3:31532521-31638548
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Drug abuse diagnoses
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_178862.3
Sequence length
4107.0 nt
GC content
0.4052

Transcripts

ID Sequence Length GC content
NM_178862.3 NCBI
GUCCCCGCCCAGCACCCCUCGCACCAGGCGGCGGCGGCGGAGGAGGAGA… 4107 nt 0.4052
Summary

The protein encoded by this gene is a catalytic subunit of a protein complex that transfers oligosaccharides onto asparagine residues. Defects in this gene are a cause of congenital disorder of glycosylation Ix (CDG1X). [provided by RefSeq, Jun 2014]

Forensic Context

A study in mice demonstrated that chronic methamphetamine administration significantly dysregulates the STT3B in microglia, which is involved in the protein processing of endoplasmic reticulum pathway [Oladapo et al. DOI:10.3390/Ijms26020649].