Basic Information

Symbol
SULT1A1
RNA class
mRNA
Alias
Sulfotransferase Family 1A Member 1 P-PST STP1 STP Sulfotransferase Family, Cytosolic, 1A, Phenol-Preferring, Member 1 Phenol-Sulfating Phenol Sulfotransferase 1 Aryl Sulfotransferase 1 Sulfotransferase 1A1 HAST1/HAST2 EC 2.8.2.1 P-PST 1 Ts-PST ST1A1 ST1A3 Thermostable Phenol Sulfotransferase1 Thermostable Phenol Sulfotransferase Phenol Sulfotransferase 1 EC 2.8.2 TSPST1 PST
Location (GRCh38)
16:28605008-28612503
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001055.4
Sequence length
1569.0 nt
GC content
0.5354

Transcripts

ID Sequence Length GC content
NM_001055.4 NCBI
ACAGUGGACCUAGGAAACCCUCAGCUCAGAGAACAACCCUGCAUUCCCC… 1569 nt 0.5354
NM_001394421.1 NCBI
GUGCCGUAGCUCGCUCGUCUCCGCCGGGGACGUGCUGCAGCAACGGCUG… 2105 nt 0.5568
NM_001394422.1 NCBI
GUGCCGUAGCUCGCUCGUCUCCGCCGGGGACGUGCUGCAGCAACGGCUG… 2904 nt 0.5610
NM_001394423.1 NCBI
GUGCCGUAGCUCGCUCGUCUCCGCCGGGGACGUGCUGCAGCAACGGCUG… 2235 nt 0.5579
NM_001394424.1 NCBI
GUGCCGUAGCUCGCUCGUCUCCGCCGGGGACGUGCUGCAGCAACGGCUG… 1802 nt 0.5544
NM_001394425.1 NCBI
GUGCCGUAGCUCGCUCGUCUCCGCCGGGGACGUGCUGCAGCAACGGCUG… 2032 nt 0.5551
NM_177529.3 NCBI
ACAGUGGACCUAGGAAACCCUCAGCUCAGAGAACAACCCUGCAUUCCCC… 1600 nt 0.5394
NM_177530.4 NCBI
ACAGUGGACCUAGGAAACCCUCAGCUCAGAGAACAACCCUGCAUUCCCC… 2441 nt 0.5494
NM_177534.4 NCBI
ACAGUGGACCUAGGAAACCCUCAGCUCAGAGAACAACCCUGCAUUCCCC… 2640 nt 0.5534
Summary

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable enzyme activity. Multiple alternatively spliced variants that encode two isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Forensic Context

A study in mice demonstrated that radiation exposure, specifically from α-particles targeting Kupffer or endothelial cells in the liver, induced a characteristic inflammatory state and altered gene expression profiles [Roudkenar et al. DOI:10.1269/jrr.07078].