Basic Information

Symbol
SULT1B1
RNA class
mRNA
Alias
Sulfotransferase Family 1B Member 1 ST1B2 Sulfotransferase Family, Cytosolic, 1B, Member 1 Thyroid Hormone Sulfotransferase Sulfotransferase 1B1 Sulfotransferase 1B2 EC 2.8.2.1 SULT1B2 ST1B1 Sulfotransferase Family Cytosolic 1B Member 1 EC 2.8.2.4 EC 2.8.2
Location (GRCh38)
4:69721167-69787961
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_014465.4
Sequence length
7018.0 nt
GC content
0.3668

Transcripts

ID Sequence Length GC content
NM_014465.4 NCBI
GAUUGCUACGUUCAGAUCAAACCUUGAACUUUUUUUUUUCUGGUGCCAG… 7018 nt 0.3668
Summary

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. However, the total genomic length of this gene is greater than that of other SULT1 genes. [provided by RefSeq, Jul 2008]

Forensic Context

A study in humans identified the SULT1B1 as a diagnostic gene marker upregulated in sepsis, with its expression validated in clinical blood samples [Chen et al. DOI:10.3389/fimmu.2025.1638156].