Basic Information

Symbol
SULT1E1
RNA class
mRNA
Alias
Sulfotransferase Family 1E Member 1 Sulfotransferase, Estrogen-Preferring EST STE Sulfotransferase Family 1E, Estrogen-Preferring, Member 1 Estrogen Sulfotransferase Sulfotransferase 1E1 EC 2.8.2.4 EST-1 ST1E1 Estrone Sulfotransferase EC 2.8.2
Location (GRCh38)
4:69838259-69861075
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_005420.3
Sequence length
1773.0 nt
GC content
0.3683

Transcripts

ID Sequence Length GC content
NM_005420.3 NCBI
AGAAGUGGUUCUCAUCUUUUUUUGCAGCUUAAGAUCUGCCUUGGUAUUU… 1773 nt 0.3683
Summary

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that transfers a sulfo moiety to and from estrone, which may control levels of estrogen receptors. [provided by RefSeq, Jul 2008] CIViC Summary for SULT1E1 Gene

Forensic Context

A study in porcine skin demonstrated that the SULT1E1 transcript was significantly decreased in all four bromine-exposed experimental groups (45 s and 8 min exposures at 24 h and 7 d post-exposure) and was involved in the xenobiotic metabolism signaling pathway [Price et al. DOI:10.1016/j.toxlet.2008.08.007].