Basic Information

Symbol
SUPT3H
RNA class
mRNA
Alias
SPT3 Homolog, SAGA And STAGA Complex Component SPT3 SPT3L Transcription Initiation Protein SPT3 Homolog SPT3-Like Protein Suppressor Of Ty 3 Homolog (S. Cerevisiae) Suppressor Of Ty (S.Cerevisiae) 3 Homolog Suppressor Of Ty 3 Homolog
Location (GRCh38)
6:44809317-45377953
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_003599.4
Sequence length
4211.0 nt
GC content
0.3740

Transcripts

ID Sequence Length GC content
NM_001261823.2 NCBI
ACACAGCCGAGUCACCUUUUCCCUUUCUACACUCCACACUCUCAGUCCC… 4120 nt 0.3745
NM_001350324.2 NCBI
ACACAGCCGAGUCACCUUUUCCCUUUCUACACUCCACACUCUCAGUCCC… 4282 nt 0.3753
NM_001350325.2 NCBI
ACACAGCCGAGUCACCUUUUCCCUUUCUACACUCCACACUCUCAGUCCC… 4205 nt 0.3741
NM_001350326.2 NCBI
GGCCACGCCCUGGCCCCGGCUCGAGGGCGGCUGCCUGGGUCUUCGUGGU… 4292 nt 0.3791
NM_001350327.2 NCBI
ACACAGCCGAGUCACCUUUUCCCUUUCUACACUCCACACUCUCAGUCCC… 4126 nt 0.3737
NM_001350329.2 NCBI
GGCCACGCCCUGGCCCCGGCUCGAGGGCGGCUGCCUGGGUCUUCGUGGU… 4203 nt 0.3781
NM_003599.4 NCBI
ACACAGCCGAGUCACCUUUUCCCUUUCUACACUCCACACUCUCAGUCCC… 4211 nt 0.3740
NM_181356.3 NCBI
ACACAGCCGAGUCACCUUUUCCCUUUCUACACUCCACACUCUCAGUCCC… 4396 nt 0.3744
Summary

Enables transcription coactivator activity. Involved in regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of SAGA complex and transcription factor TFTC complex. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in humans analyzing leukocyte gene expression profiles from severe burn patients identified the SUPT3H as a transcription factor with sustained increased expression post-burn, suggesting it may be a driver for inducing an immunosuppressive state during recovery [Xu et al. DOI:10.1159/000493451].