Basic Information

Symbol
SV2A
RNA class
mRNA
Alias
Synaptic Vesicle Glycoprotein 2A KIAA0736 SLC22B1 SV2 Solute Carrier Family 22 Member B1 DEE113
Location (GRCh38)
1:149903318-149918572
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Drug abuse diagnoses
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_014849.5
Sequence length
4378.0 nt
GC content
0.5450

Transcripts

ID Sequence Length GC content
NM_001328674.2 NCBI
GCAUUGCCGCUUCCCUGGUGCCGGGAGCAGUCGCCGCUGCCGCCUCCGC… 4204 nt 0.5440
NM_001328675.2 NCBI
GCAUUGCCGCUUCCCUGGUGCCGGGAGCAGUCGCCGCUGCCGCCUCCGC… 4160 nt 0.5447
NM_014849.5 NCBI
GCAUUGCCGCUUCCCUGGUGCCGGGAGCAGUCGCCGCUGCCGCCUCCGC… 4378 nt 0.5450
Summary

The protein encoded by this gene is one of three related synaptic vesicle proteins. The encoded protein may interact with synaptotagmin to enhance low frequency neurotransmission in quiescent neurons. [provided by RefSeq, Jun 2016]

Forensic Context

A study in rats demonstrated that chronic methamphetamine administration significantly altered the expression of 40 miRNAs and three novel miRNAs in the nucleus accumbens, validated by qPCR, and induced pathological neuronal changes and addiction-like behavior [Yang et al. DOI:10.1080/13880209.2020.1803366].