Basic Information

Symbol
SYCP2
RNA class
mRNA
Alias
Synaptonemal Complex Protein 2 SCP2 Synaptonemal Complex Lateral Element Protein SCP-2 HsSCP2 SPGF1
Location (GRCh38)
20:59863564-59933655
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_014258.4
Sequence length
5541.0 nt
GC content
0.3429

Transcripts

ID Sequence Length GC content
NM_014258.4 NCBI
GCAGAGUUGCGACGCUCGGCGGCAUAGGGGGCGGCUCCACCGACACUAC… 5541 nt 0.3429
Summary

The synaptonemal complex is a proteinaceous structure that links homologous chromosomes during the prophase of meiosis. The protein encoded by this gene is a major component of the synaptonemal complex and may bind DNA at scaffold attachment regions. The encoded protein requires synaptonemal complex protein 3, but not 1, for inclusion in the synaptonemal complex. [provided by RefSeq, Jul 2008]

Forensic Context

A study in human sepsis patients identified the SYCP2 as a potential diagnostic biomarker, where it was found to be differentially expressed with a consistent mRNA and corresponding protein expression pattern in the sepsis group compared to healthy controls [Wang et al. DOI:10.2147/IDR.S380137].