Basic Information
MANE select
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| GGGUGGAGUCGGGCGGGGCGCCGGGCAGGUUCCUCUGCGUUCCGCGGCG… | 1635 nt | 0.6073 | |
| GGGUGGAGUCGGGCGGGGCGCCGGGCAGGUUCCUCUGCGUUCCGCGGCG… | 1864 nt | 0.6084 | |
| GCGUUCCGCGGCGGCGGCAGCGGCGGCGACGGCGACAUGGAGAGCGGGG… | 1495 nt | 0.6127 |
Summary
This gene encodes an integral membrane protein containing four transmembrane regions and a C-terminal cytoplasmic tail that is tyrosine phosphorylated. The exact function of this protein is unclear, but studies of a similar rat protein suggest that it may play a role in regulating membrane traffic in non-neuronal cells. The gene belongs to the synaptogyrin gene family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Forensic Context
A study in mice demonstrated that synaptogyrin 2 (Syngr2) gene expression was down-regulated specifically in liver tissue following neutron exposure, as identified through oligonucleotide microarray analysis and validated by real-time PCR [Roudkenar et al. DOI:10.1269/jrr.07078].