Basic Information
Symbol
SYNGR3
RNA class
mRNA
Alias
Synaptogyrin 3
Synaptogyrin-3
Location (GRCh38)
16:1989660-1994275
Forensic tag(s)
Other applications
MANE select
Transcript ID
NM_004209.6
Sequence length
2026.0 nt
GC content
0.6397
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| GAGGCGGCAGCGGCUGCAGCGUUGGUAGCAUCAGCAUCAGCAUCAGCGG… | 2026 nt | 0.6397 |
Summary
This gene encodes an integral membrane protein. The exact function of this protein is unclear, but studies of a similar murine protein suggest that it is a synaptic vesicle protein that also interacts with the dopamine transporter. The gene product belongs to the synaptogyrin gene family. [provided by RefSeq, Dec 2010]
Forensic Context
A study in mice demonstrated that chronic alcohol exposure significantly downregulated SYNGR3 mRNA expression in hippocampal tissue, as identified through high-throughput sequencing and bioinformatic network analysis [Du et al. DOI:10.3389/Fphar.2024.1377501].