Basic Information

Symbol
SYNPO
RNA class
mRNA
Alias
Synaptopodin KIAA1029 SYNPO1
Location (GRCh38)
5:150601080-150659208
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_007286.6
Sequence length
5359.0 nt
GC content
0.6094

Transcripts

ID Sequence Length GC content
NM_001109974.3 NCBI
GAUAAAGAGCUGGGCUGAGUCAUCUGUGGAGGAGAAAAGUCACAUCCAG… 6484 nt 0.5762
NM_001166208.2 NCBI
AGACAGAGCGCGAGUGAGGAGCAGGCGGGCAGGCGGCGGGCAGCCGGGC… 7067 nt 0.5845
NM_001166209.2 NCBI
AGUUUGCAUCUUAGGUCACACCACUCCUGUGAUUCCUGUGGUAUUGCCC… 6996 nt 0.5818
NM_007286.6 NCBI
GAUAAAGAGCUGGGCUGAGUCAUCUGUGGAGGAGAAAAGUCACAUCCAG… 5359 nt 0.6094
Summary

Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. The name synaptopodin derives from the protein's associations with postsynaptic densities and dendritic spines and with renal podocytes (Mundel et al., 1997 [PubMed 9314539]).[supplied by OMIM, Mar 2008]

Forensic Context

A study in humans demonstrated that the SYNPO gene was downregulated in subcutaneous adipose tissue during short-term weight loss [Bollepalli et al. DOI:10.1038/ijo.2017.245].