Basic Information

Symbol
TAOK3
RNA class
mRNA
Alias
TAO Kinase 3 MAP3K18 JIK DPK Cutaneous T-Cell Lymphoma-Associated Antigen HD-CL-09 Dendritic Cell-Derived Protein Kinase Thousand And One Amino Acid Protein 3 Serine/Threonine-Protein Kinase TAO3 CTCL-Associated Antigen HD-CL-09 Kinase From Chicken Homolog A Jun Kinase-Inhibitory Kinase JNK/SAPK-Inhibitory Kinase EC 2.7.11.1 HKFC-A STE20-Like Kinase EC 2.7.11 KDS
Location (GRCh38)
12:118149801-118372920
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_016281.4
Sequence length
4346.0 nt
GC content
0.4429

Transcripts

ID Sequence Length GC content
NM_001346487.2 NCBI
AGGAGCCGCACCUCGGACAGCAGCAGCGGCGGCGGCCGCGGGAGGGUCC… 4373 nt 0.4434
NM_001346488.2 NCBI
AGGAGCCGCACCUCGGACAGCAGCAGCGGCGGCGGCCGCGGGAGGGUCC… 4523 nt 0.4435
NM_001346489.2 NCBI
ACUUCAGCUUGCAAUACUGAUAGUAAUGUGUGGCACCCAGAUCACGCUG… 4286 nt 0.4200
NM_001346490.2 NCBI
AGGAGCCGCACCUCGGACAGCAGCAGCGGCGGCGGCCGCGGGAGGGUCC… 5272 nt 0.4274
NM_001346491.2 NCBI
AGGAGCCGCACCUCGGACAGCAGCAGCGGCGGCGGCCGCGGGAGGGUCC… 5422 nt 0.4279
NM_001346492.2 NCBI
AGGAGCCGCACCUCGGACAGCAGCAGCGGCGGCGGCCGCGGGAGGGUCC… 5245 nt 0.4269
NM_001346493.2 NCBI
AGGAGCCGCACCUCGGACAGCAGCAGCGGCGGCGGCCGCGGGAGGGUCC… 4234 nt 0.4410
NM_001346494.2 NCBI
AGAACUGUGUACGAUCAUGACUGGAAAGCAGGAUCCCUCAGUGACUGCC… 3293 nt 0.4248
NM_001346495.2 NCBI
AGAACUGUGUACGAUCAUGACUGGAAAGCAGGAUCCCUCAGUGACUGCC… 3052 nt 0.4197
NM_001346496.2 NCBI
AGAACUGUGUACGAUCAUGACUGGAAAGCAGGAUCCCUCAGUGACUGCC… 2282 nt 0.4500
Showing 1 to 10 of 12 entries
Summary

The protein encoded by this gene is a serine/threonine protein kinase that activates the p38/MAPK14 stress-activated MAPK cascade but inhibits the basal activity of the MAPK8/JNK cascade. The encoded protein is a member of the GCK subfamily of STE20-like kinases. [provided by RefSeq, Oct 2016]

Forensic Context

A longitudinal mRNA expression analysis in post-mortem human blood samples identified two groups of up- and down-regulated genes, with pathway analysis indicating active processes promoting cell survival and DNA damage repair shortly after death [Antiga et al. DOI:10.1038/s41598-021-96095-z].