Basic Information

Symbol
TBC1D17
RNA class
mRNA
Alias
TBC1 Domain Family Member 17 FLJ12168 TBC1 Domain Family, Member 17
Location (GRCh38)
19:49877501-49888751
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Drug abuse diagnoses
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_024682.3
Sequence length
2095.0 nt
GC content
0.6286

Transcripts

ID Sequence Length GC content
NM_001168222.2 NCBI
AGUGGGGCCUUCGGCGGCGACUAUGGAAGGAGCCGGCUACAGGGACAAU… 1996 nt 0.6328
NM_024682.3 NCBI
AGUGGGGCCUUCGGCGGCGACUAUGGAAGGAGCCGGCUACAGGGUGGUG… 2095 nt 0.6286
Summary

Predicted to enable GTPase activator activity. Involved in retrograde transport, endosome to Golgi. Located in cytosol. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in mice demonstrated that chronic methamphetamine administration significantly dysregulates the TBC1D17 in microglia, where it is involved in the mitophagy pathway [Oladapo et al. DOI:10.3390/Ijms26020649].