Basic Information

Symbol
TBX15
RNA class
mRNA
Alias
T-Box Transcription Factor 15 TBX14 T-Box Transcription Factor TBX15 T-Box Transcription Factor TBX14 T-Box Protein 14 T-Box Protein 15 T-Box 14 T-Box 15
Location (GRCh38)
1:118883046-118989556
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001330677.2
Sequence length
4042.0 nt
GC content
0.5054

Transcripts

ID Sequence Length GC content
NM_001330677.2 NCBI
CCCCCUCCCUCUCCCUCACCCCUCGGACAGGAGCGCACCGCCUGCCCCC… 4042 nt 0.5054
NM_152380.3 NCBI
ACUAGGACUGGAAGAUCGGGCUGUGUCUAGGCCGCUGUCCGCGAAAUCC… 3445 nt 0.4801
Summary

This gene belongs to the T-box family of genes, which encode a phylogenetically conserved family of transcription factors that regulate a variety of developmental processes. All these genes contain a common T-box DNA-binding domain. Mutations in this gene are associated with Cousin syndrome.[provided by RefSeq, Oct 2009]

Forensic Context

A study in rats demonstrated that the TBX15 was core-enriched in upregulated developmental gene sets in fetal cardiac fibroblasts compared with neonatal cardiac fibroblasts, indicating its role in age-dependent transcriptional programming [Perreault et al. DOI:10.1152/physiolgenomics.00074.2021].