Basic Information

Symbol
TCF20
RNA class
mRNA
Alias
Transcription Factor 20 SPBP AR1 Stromelysin-1 Platelet-Derived Growth Factor-Responsive Element Binding Protein Stromelysin-1 PDGF-Responsive Element-Binding Protein SPRE-Binding Protein Nuclear Factor SPBP TCF-20 Transcription Factor 20 (AR1) Protein AR1 KIAA0292 DDVIBA
Location (GRCh38)
22:42160013-42343616
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001378418.1
Sequence length
7624.0 nt
GC content
0.5186

Transcripts

ID Sequence Length GC content
NM_001378418.1 NCBI
GUUAUUUCCUGUGUGUUGGGAGAAUGGAGAGAAAAAACCCCGAGCCCAG… 7624 nt 0.5186
NM_005650.4 NCBI
CCUCCUCCCCCGCCUCGGCUCAGGAGUUGUUUUCCUCCCCCGUGGUCGC… 7410 nt 0.5089
NM_181492.3 NCBI
GUUAUUUCCUGUGUGUUGGGAGAAUGGAGAGAAAAAACCCCGAGCCCAG… 7496 nt 0.5164
Summary

This gene encodes a transcription factor that recognizes the platelet-derived growth factor-responsive element in the matrix metalloproteinase 3 promoter. The encoded protein is thought to be a transcriptional coactivator, enhancing the activity of transcription factors such as JUN and SP1. Mutations in this gene are associated with autism spectrum disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

Forensic Context

No relevant information is available at the moment.