Basic Information

Symbol
TDRD1
RNA class
mRNA
Alias
Tudor Domain Containing 1 CT41.1 Cancer/Testis Antigen 41.1 Tudor Domain-Containing Protein 1 Testicular Tissue Protein Li 193
Location (GRCh38)
10:114179270-114232666
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001395205.1
Sequence length
8149.0 nt
GC content
0.3971

Transcripts

ID Sequence Length GC content
NM_001365891.2 NCBI
AGUCGCCAUCACCGCCAGACCGCAGAGACAGGCCUCGAUGAGUGUUAAA… 4749 nt 0.3925
NM_001385363.1 NCBI
GCACUGGGGAUUGGAGGCGAGGGAAGUGCAGGGCGCAUCCCAGGCGGCA… 4822 nt 0.3973
NM_001385364.2 NCBI
AGUCGCCAUCACCGCCAGACCGCAGAGACAGGUUCGGAUCCGCGGUCCU… 4794 nt 0.3942
NM_001385365.1 NCBI
GCACUGGGGAUUGGAGGCGAGGGAAGUGCAGGGCGCAUCCCAGGCGGCA… 4767 nt 0.4019
NM_001385366.1 NCBI
GCACUGGGGAUUGGAGGCGAGGGAAGUGCAGGGCGCAUCCCAGGCGGCA… 8044 nt 0.3994
NM_001385367.1 NCBI
GCACUGGGGAUUGGAGGCGAGGGAAGUGCAGGGCGCAUCCCAGGCGGCA… 4627 nt 0.4013
NM_001385368.1 NCBI
GCACUGGGGAUUGGAGGCGAGGGAAGUGCAGGGCGCAUCCCAGGCGGCA… 4632 nt 0.4011
NM_001385369.1 NCBI
GCACUGGGGAUUGGAGGCGAGGGAAGUGCAGGGCGCAUCCCAGGCGGCA… 7987 nt 0.4012
NM_001385370.1 NCBI
GCACUGGGGAUUGGAGGCGAGGGAAGUGCAGGGCGCAUCCCAGGCGGCA… 7873 nt 0.3997
NM_001385371.1 NCBI
GCACUGGGGAUUGGAGGCGAGGGAAGUGCAGGGCGCAUCCCAGGCGGCA… 7843 nt 0.4020
Showing 1 to 10 of 13 entries
Summary

This gene encodes a protein containing a tudor domain that is thought to function in the suppression of transposable elements during spermatogenesis. The related protein in mouse forms a complex with piRNAs and Piwi proteins to promote methylation and silencing of target sequences. This gene was observed to be upregulated by ETS transcription factor ERG in prostate tumors. [provided by RefSeq, Sep 2018]

Forensic Context

A study in humans identified the TDRD1 as a potential biomarker for sepsis diagnosis, where it was found to be lowly expressed in the sepsis group based on RNA sequencing data and its mRNA expression pattern was consistent with its corresponding protein according to nine-quadrant analysis [Wang et al. DOI:10.2147/IDR.S380137].