Basic Information

Symbol
TET2
RNA class
mRNA
Alias
Tet Methylcytosine Dioxygenase 2 KIAA1546 Methylcytosine Dioxygenase TET2 Tet Oncogene Family Member 2 Ten-Eleven Translocation 2 FLJ20032 Probable Methylcytosine Dioxygenase TET2 EC 1.14.11.80 EC 1.14.11.N2 IMD75 MDS
Location (GRCh38)
4:105145875-105279816
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001127208.3
Sequence length
9589.0 nt
GC content
0.4115

Transcripts

ID Sequence Length GC content
NM_001127208.3 NCBI
GUAGAGAAGCAGAAGGAAGCAAGAUGGCUGCCCUUUAGGAUUUGUUAGA… 9589 nt 0.4115
NM_017628.4 NCBI
AAACAGAAGGUGGGCCGGGGCGGGGAGAAACAGAACUCGGUCAAUUUCC… 9236 nt 0.3952
Summary

The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] CIViC Summary for TET2 Gene

Forensic Context

No relevant information is available at the moment.