Basic Information

Symbol
THBS3
RNA class
mRNA
Alias
Thrombospondin 3 Thrombospondin-3 TSP3
Location (GRCh38)
1:155195587-155209051
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_007112.5
Sequence length
3145.0 nt
GC content
0.5583

Transcripts

ID Sequence Length GC content
NM_001252607.2 NCBI
GUAGUGAGCCGGCUGAGAGGCAUGGAGACGCAGGAACUUCGGGGGGCCC… 3118 nt 0.5590
NM_001252608.2 NCBI
GUAGUGAGCCGGCUGAGAGGCAUGGAGACGCAGGAACUUCGGGGGGCCC… 2785 nt 0.5548
NM_001407487.1 NCBI
GUAGUGAGCCGGCUGAGAGGCAUGGAGACGCAGGAACUUCGGGGGGCCC… 3154 nt 0.5583
NM_001407488.1 NCBI
GUAGUGAGCCGGCUGAGAGGCAUGGAGACGCAGGAACUUCGGGGGGCCC… 3005 nt 0.5607
NM_001407490.1 NCBI
GUAGUGAGCCGGCUGAGAGGCAUGGAGACGCAGGAACUUCGGGGGGCCC… 3972 nt 0.5642
NM_001407554.1 NCBI
GUAGUGAGCCGGCUGAGAGGCAUGGAGACGCAGGAACUUCGGGGGGCCC… 3055 nt 0.5571
NM_001407555.1 NCBI
GUAGUGAGCCGGCUGAGAGGCAUGGAGACGCAGGAACUUCGGGGGGCCC… 3034 nt 0.5587
NM_001407556.1 NCBI
ACCGCCCCUCCGAUCGUUGCGGUCAGGGGGCCUGGGGAGAUCCCCGGGG… 3318 nt 0.5729
NM_001407557.1 NCBI
ACCGCCCCUCCGAUCGUUGCGGUCAGGGGGCCUGGGGAGAUCCCCGGGG… 3416 nt 0.5735
NM_001407558.1 NCBI
ACCGCCCCUCCGAUCGUUGCGGUCAGGGGGCCUGGGGAGAUCCCCGGGG… 3207 nt 0.5737
Showing 1 to 10 of 15 entries
Summary

The protein encoded by this gene belongs to the thrombospondin family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentameric molecule linked by a single disulfide bond. This gene shares a common promoter with metaxin 1. Alternate splicing results in coding and non-coding transcript variants. [provided by RefSeq, Nov 2011]

Forensic Context

A study in porcine skin demonstrated that the THBS3 was significantly decreased at 7 days postexposure to sulfur mustard [Price et al. DOI:10.080/15569520903097754].