Basic Information

Symbol
THBS3
RNA class
mRNA
Alias
Thrombospondin 3 Thrombospondin-3 TSP3
Location (GRCh38)
1:155195587-155209051
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_007112.5
Sequence length
3145.0 nt
GC content
0.5583

Transcripts

ID Sequence Length GC content
NM_001407559.1 NCBI
ACCGCCCCUCCGAUCGUUGCGGUCAGGGGGCCUGGGGAGAUCCCCGGGG… 3325 nt 0.5729
NM_001407560.1 NCBI
GUAGUGAGCCGGCUGAGAGGCAUGGAGACGCAGGAACUUCGGGGGGCCC… 3062 nt 0.5575
NM_001407561.1 NCBI
ACCGCCCCUCCGAUCGUUGCGGUCAGGGGGCCUGGGGAGAUCCCCGGGG… 3215 nt 0.5739
NM_001407562.1 NCBI
GUAGUGAGCCGGCUGAGAGGCAUGGAGACGCAGGAACUUCGGGGGGCCC… 3138 nt 0.5580
NM_007112.5 NCBI
GUAGUGAGCCGGCUGAGAGGCAUGGAGACGCAGGAACUUCGGGGGGCCC… 3145 nt 0.5583
Showing 11 to 15 of 15 entries
Summary

The protein encoded by this gene belongs to the thrombospondin family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentameric molecule linked by a single disulfide bond. This gene shares a common promoter with metaxin 1. Alternate splicing results in coding and non-coding transcript variants. [provided by RefSeq, Nov 2011]

Forensic Context

A study in porcine skin demonstrated that the THBS3 was significantly decreased at 7 days postexposure to sulfur mustard [Price et al. DOI:10.080/15569520903097754].