Basic Information

Symbol
THSD7B
RNA class
mRNA
Alias
Thrombospondin Type 1 Domain Containing 7B KIAA1679 Thrombospondin Type-1 Domain-Containing Protein 7B Thrombospondin, Type I, Domain Containing 7B
Location (GRCh38)
2:136765545-137677718
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl UniProt GTEx

MANE select

Transcript ID
NM_001316349.2
Sequence length
6112.0 nt
GC content
0.4720

Transcripts

ID Sequence Length GC content
NM_001316349.2 NCBI
AGUGCUGAGGAGCCAGAGUCGCCGCCGGGUUGCCAGACGCUGGAAUGGG… 6112 nt 0.4720
Summary

Predicted to be involved in actin cytoskeleton organization. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in rhesus macaques identified the THSD7B as a shared upregulated differentially expressed gene between affected animals and adult human patients with hypertrophic cardiomyopathy, establishing its association with this cardiac disease in this non-human primate model [Rivas et al. DOI:10.1038/s41598-024-82770-4].