Basic Information

Symbol
TIAM2
RNA class
mRNA
Alias
TIAM Rac1 Associated GEF 2 STEF T-Lymphoma Invasion And Metastasis-Inducing Protein 2 Rho Guanine Nucleotide Exchange Factor TIAM2 Sif And Tiam1-Like Exchange Factor TIAM-2 T-Cell Lymphoma Invasion And Metastasis 2 T Cell Lymphoma Invasion And Metastasis 2 SIF And TIAM1-Like Exchange Factor KIAA2016
Location (GRCh38)
6:154832697-155257723
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_012454.4
Sequence length
6094.0 nt
GC content
0.4977

Transcripts

ID Sequence Length GC content
NM_001010927.3 NCBI
AUUGCCUGGGGAUGAGAGGGAGAGACAACGUGUGUCUUACACAUCUCCC… 2665 nt 0.4514
NM_001384546.1 NCBI
AGAAAAGGCUGGAGUCCCAGUCCGUGGAGGAGCACUUACAGGGUCUUUC… 5976 nt 0.4910
NM_001384547.1 NCBI
CUGUUUUUAGCUCUCAACGGCUGAGCAUUUGAAGUGUUAGACACUGUUU… 6002 nt 0.4890
NM_012454.4 NCBI
AGCGGUAACCGUAACUGUGGCCGCGGCCGCCGCAGGCGCACAGCGCGCG… 6094 nt 0.4977
Summary

This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Forensic Context

No relevant information is available at the moment.