Basic Information

Symbol
TIMM9
RNA class
mRNA
Alias
Translocase Of Inner Mitochondrial Membrane 9 TIM9A Mitochondrial Import Inner Membrane Translocase Subunit Tim9 TIM9 Translocase Of Inner Mitochondrial Membrane 9 (Yeast) Homolog Translocase Of Inner Mitochondrial Membrane 9 Homolog (Yeast) Translocase Of Inner Mitochondrial Membrane 9 Homolog TIMM9A
Location (GRCh38)
14:58407461-58427655
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_012460.4
Sequence length
1252.0 nt
GC content
0.4129

Transcripts

ID Sequence Length GC content
NM_001304485.2 NCBI
AAGGUAGCACAUUGCCGCACAAGACCGCUCUACAGUCUCAUCCAAGACU… 1063 nt 0.3866
NM_001304486.1 NCBI
AUUUCCUCGCGUUAUAACGAAUCGGCGUCUAAGGGUUUAAGUGUCACUU… 1029 nt 0.4004
NM_001304487.2 NCBI
AAGGUAGCACAUUGCCGCACAAGACCGCUCUACAGUCUCAUCCAAGACU… 975 nt 0.3856
NM_001304488.1 NCBI
AUUUCCUCGCGUUAUAACGAAUCGGCGUCUAAGGGUUUAAGUGUCACUU… 1048 nt 0.4055
NM_001304489.1 NCBI
AUUUCCUCGCGUUAUAACGAAUCGGCGUCUAAGGGUUUAAGUGUCACUU… 1033 nt 0.4076
NM_001304490.1 NCBI
AUUUCCUCGCGUUAUAACGAAUCGGCGUCUAAGGGUUUAAGUGUCACUU… 1030 nt 0.4068
NM_001304491.1 NCBI
AUUUCCUCGCGUUAUAACGAAUCGGCGUCUAAGGGUUUAAGUGUCACUU… 942 nt 0.4076
NM_012460.4 NCBI
AAGGUAGCACAUUGCCGCACAAGACCGCUCUACAGUCUCAUCCAAGACU… 1252 nt 0.4129
Summary

TIMM9 belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane.[supplied by OMIM, Apr 2004]

Forensic Context

A study in mice demonstrated that the TIMM9 was down-regulated in brain tissue at 8 hours (0.494-fold) and 24 hours (0.482-fold) following whole-body irradiation with 10 Gy γ-rays, identifying it as a protein transport/folding marker responsive to ionizing radiation [Zhao et al. DOI:10.1158/1078-0432.CCR-05-2418].