Basic Information

Symbol
TINAGL1
RNA class
mRNA
Alias
Tubulointerstitial Nephritis Antigen Like 1 TINAGRP P3ECSL LIECG3 ARG1 LCN7 Tubulointerstitial Nephritis Antigen-Related Protein Tubulointerstitial Nephritis Antigen-Like Glucocorticoid-Inducible Protein 5 TIN Ag-Related Protein TINAG-Like 1 Lipocalin 7 TIN-Ag-RP OLRG-2 Oxidized LDL-Responsive Gene 2 Protein Oxidized-LDL Responsive Gene 2 Androgen Regulated Gene 1 Androgen-Regulated Gene 1 TINAGL OLRG2 GIS5
Location (GRCh38)
1:31576485-31587689
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_022164.3
Sequence length
2207.0 nt
GC content
0.6180

Transcripts

ID Sequence Length GC content
NM_001204414.2 NCBI
GACUUUGAGCGUCCGGCGGUCGCAGAGCCAGGAGGCGGAGGCGCGCGGG… 2114 nt 0.6211
NM_001204415.2 NCBI
GAAUCCAGGUUGGAAUCAUUGAAGAACUUCCCAAACAGCAGUUGGAUGU… 1845 nt 0.5962
NM_022164.3 NCBI
GACUUUGAGCGUCCGGCGGUCGCAGAGCCAGGAGGCGGAGGCGCGCGGG… 2207 nt 0.6180
Summary

The protein encoded by this gene is similar in sequence to tubulointerstitial nephritis antigen, a secreted glycoprotein that is recognized by antibodies in some types of immune-related tubulointerstitial nephritis. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]

Forensic Context

A study in human burn patients demonstrated that early peripheral blood mononuclear cell expression of the TINAGL1 was significantly increased compared to healthy controls and strongly correlated with burn severity, acute lung injury, pulmonary infection, and mortality [Cressida Mahung et al. DOI:10.1097/TA.0000000000003602]. A study in human burn patients demonstrated that early peripheral blood mononuclear cell expression of the TINAGL1 was significantly increased compared to healthy controls and strongly correlated with burn severity, acute lung injury, pulmonary infection, and mortality [Mahung et al. DOI:10.1097/TA.0000000000003602].