Basic Information

Symbol
TLCD2
RNA class
mRNA
Alias
TLC Domain Containing 2 TLC Domain-Containing Protein 2
Location (GRCh38)
17:1702816-1710377
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001164407.2
Sequence length
5884.0 nt
GC content
0.4990

Transcripts

ID Sequence Length GC content
NM_001164407.2 NCBI
GCUGAUCCCAAAGGCGCGGCGGGGAGGGGAGCCGGGGCCCCAGCCCUGC… 5884 nt 0.4990
Summary

Involved in several processes, including membrane assembly; phospholipid homeostasis; and regulation of membrane lipid distribution. Located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in human cardiac tissue from forensic autopsies demonstrated that the TLCD2 mRNA was downregulated in the mechanical asphyxia group compared to the craniocerebral injury group, identifying it as a potential biomarker for mechanical asphyxia [Zeng et al. DOI:10.1007/S00414-017-1616-4].