Basic Information

Symbol
TMBIM1
RNA class
mRNA
Alias
Transmembrane BAX Inhibitor Motif Containing 1 RECS1 LFG3 PP1201 Transmembrane BAX Inhibitor Motif-Containing Protein 1 Protein Lifeguard 3 Protein RECS1 Homolog MSTP100 MST100
Location (GRCh38)
2:218274194-218292586
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_022152.6
Sequence length
2292.0 nt
GC content
0.5327

Transcripts

ID Sequence Length GC content
NM_001321427.2 NCBI
AGUACACAUACUCUCCUCUUGCUGUAACCCCAGUAGCUCAGGCCUCCUC… 2871 nt 0.5385
NM_001321428.2 NCBI
AGUUCCAAACCCAUGACGAAGAAGAGGGCUGUUCUGGGGUGGAGCAGGA… 2345 nt 0.5296
NM_001321429.2 NCBI
AGUUCCAAACCCAUGACGAAGAAGAGGGCUGUUCUGGGGUGGAGCAGGA… 2521 nt 0.5359
NM_001321430.2 NCBI
CUGGAUUCCUGCAGCUAGUUCAUGAACCCAGGCAGAUGCCAGCCCCAAA… 2461 nt 0.5364
NM_001321432.2 NCBI
CUGGAUUCCUGCAGCUAGUUCAUGAACCCAGGUCCCAGCAGCUGGGGUU… 2285 nt 0.5300
NM_001321433.2 NCBI
ACUCCGAGGCCAGGAACGCUCCGUCUGGAACGGCGCAGGCUGGAGUACG… 2390 nt 0.5351
NM_001321435.2 NCBI
ACUCCGAGGCCAGGAACGCUCCGUCUGGAACGGCGCAGAUGCCAGCCCC… 2464 nt 0.5386
NM_001321436.2 NCBI
ACUCCGAGGCCAGGAACGCUCCGUCUGGAACGGCGCAGGCAGAUGCCAG… 2468 nt 0.5389
NM_001321438.2 NCBI
ACUCCGAGGCCAGGAACGCUCCGUCUGGAACGGCGCAGGUCCCAGCAGC… 2227 nt 0.5344
NM_022152.6 NCBI
ACUCCGAGGCCAGGAACGCUCCGUCUGGAACGGCGCAGGUCCCAGCAGC… 2292 nt 0.5327
Summary

Enables death receptor binding activity. Involved in negative regulation of Fas signaling pathway; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; and negative regulation of protein localization to plasma membrane. Located in Golgi membrane; endosome membrane; and lysosomal membrane. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

No relevant information is available at the moment.