Basic Information

Symbol
TMEM100
RNA class
mRNA
Alias
Transmembrane Protein 100 FLJ10970 FLJ37856
Location (GRCh38)
17:55718739-55732121
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_018286.3
Sequence length
1755.0 nt
GC content
0.4085

Transcripts

ID Sequence Length GC content
NM_001099640.2 NCBI
AGCCUUGUUGGUCCCGCGGUACAUGCUUCCUGUUCCCAGAGAGAUUCAC… 2213 nt 0.4239
NM_018286.3 NCBI
GUCAUUUAGGAACAGAGGUAGCCUGAAAGAAGCAGGAACUCCAGGAUCC… 1755 nt 0.4085
Summary

Involved in BMP signaling pathway. Located in several cellular components, including endoplasmic reticulum; perikaryon; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in humans demonstrated that the TMEM100 was the most upregulated gene in subcutaneous adipose tissue during short-term (0-5 month) weight loss in obese participants, and its expression pattern was reciprocal to that observed in acquired obesity within BMI-discordant monozygotic twin pairs [Bollepalli et al. DOI:10.1038/ijo.2017.245].