Basic Information
Symbol
TMEM170B
RNA class
mRNA
Alias
Transmembrane Protein 170B
Location (GRCh38)
6:11537748-11583524
Forensic tag(s)
Cause of death analysis
MANE select
Transcript ID
NM_001100829.3
Sequence length
8891.0 nt
GC content
0.3732
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| CCUCGAGUGUCGGCGACCCGAGGGCGGGCAGGCGGGCGGCAGGUGCCGC… | 8891 nt | 0.3732 |
Summary
Involved in negative regulation of canonical Wnt signaling pathway. Located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Forensic Context
A study in humans identified the TMEM170B as a significantly increased mRNA in sepsis patients compared to controls, and it was regulated by most differentially expressed miRNAs and enriched in the T cell receptor signaling pathway and influenza A pathway [Qin et al. DOI:10.1097/JCMA.0000000000000209].