Basic Information

Symbol
TMSB10
RNA class
mRNA
Alias
Thymosin Beta 10 TB10 Thymosin Beta-10 Migration-Inducing Protein 12 Migration-Inducing Gene 12 PTMB10 THYB10 MIG12
Location (GRCh38)
Forensic tag(s)
Other applications

MANE select

Transcript ID
NM_021103.4
Sequence length
461.0 nt
GC content
0.5336

Transcripts

ID Sequence Length GC content
GUUUCUUGCUGCAGCAACGCGAGUGGGAGCACCAGGAUCUCGGGCUCGG… 461 nt 0.5336
Summary

Predicted to enable actin monomer binding activity. Predicted to be involved in regulation of cell migration. Predicted to be located in cytoskeleton. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in mice demonstrated that the TMSB10 was identified as a gene expression marker with a potential key role in separating low- and high-functioning aged groups following laparotomy, showing differentially expressed patterns with reversed regulation between these groups [Asche-Godin et al. DOI:10.1093/gerona/glac043]. In a separate study in rats, the TMSB10 was listed among the top five differentially expressed genes upregulated in the spinal cord at 3 and 7 days following a tibial fracture [Deng et al. DOI:10.1038/s41598-025-17561-6].