Basic Information

Symbol
TNFRSF17
RNA class
mRNA
Alias
TNF Receptor Superfamily Member 17 BCM TNFRSF13A CD269 BCMA Tumor Necrosis Factor Receptor Superfamily Member 17 B-Cell Maturation Protein Tumor Necrosis Factor Receptor Superfamily, Member 17 B Cell Maturation Antigen B-Cell Maturation Factor CD269 Antigen
Location (GRCh38)
16:11965210-11968068
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001192.3
Sequence length
891.0 nt
GC content
0.4153

Transcripts

ID Sequence Length GC content
NM_001192.3 NCBI
AUUGUUCUCAACAUUCUAGCUGCUCUUGCUGCAUUUGCUCUGGAAUUCU… 891 nt 0.4153
Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008] CIViC Summary for TNFRSF17 Gene

Forensic Context

A study in human trauma patients demonstrated that TNFRSF17 mRNA was significantly downregulated in circulating CD3+ T cells during the injury stage compared to the recovery stage [Rau et al. DOI:10.2147/JIR.S375881].