TNFAIP3 Interacting Protein 1
ABIN-1
NAF1
VAN
KIAA0113
A20-Binding Inhibitor Of NF-Kappa-B Activation 1
Virion-Associated Nuclear Shuttling Protein
TNFAIP3-Interacting Protein 1
HIV-1 Nef-Interacting Protein
Nef-Associated Factor 1 SNP
Nip40-1
Virion-Associated Nuclear-Shuttling Protein
Nef-Associated Factor 1
Naf1
HVAN
This gene encodes an A20-binding protein which plays a role in autoimmunity and tissue homeostasis through the regulation of nuclear factor kappa-B activation. Mutations in this gene have been associated with psoriatic arthritis, rheumatoid arthritis, and systemic lupus erythematosus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Forensic Context
A study in humans demonstrated that the TNIP1 was downregulated during long-term weight loss (0 to 12 months) in weight losers within subcutaneous adipose tissue [Bollepalli et al. DOI:10.1038/ijo.2017.245].