Basic Information

Symbol
TOGARAM1
RNA class
mRNA
Alias
TOG Array Regulator Of Axonemal Microtubules 1 Crescerin-1 KIAA0423 Crescerin FAM179B TOG Array Regulator Of Axonemal Microtubules Protein 1 Family With Sequence Similarity 179 Member B Protein FAM179B Family With Sequence Similarity 179, Member B JBTS37
Location (GRCh38)
Forensic tag(s)
Other applications

MANE select

Transcript ID
NM_001308120.2
Sequence length
6424.0 nt
GC content
0.4197

Transcripts

ID Sequence Length GC content
ACGUGGUGCCCUUGGUUACGCCCGGUGGCAGCUGUGGGGUCUAGGGCUC… 6424 nt 0.4197
ACGUGGUGCCCUUGGUUACGCCCGGUGGCAGCUGUGGGGUCUAGGGCUC… 6265 nt 0.4200
Summary

Predicted to enable microtubule binding activity. Involved in cilium assembly. Located in axoneme. Implicated in Joubert syndrome. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in mice demonstrated that acute alcohol exposure during neurulation induces short-term transcriptomic changes in the rostroventral neural tube, where the TOGARAM1 was down-regulated (-0.32 Log2FC) 2 hours post-exposure, indicating its role in cilia-related processes and the regulation of mitosis [Boschen et al. DOI:10.1016/J.Alcohol.2022.09.001].