Basic Information

Symbol
TOMM34
RNA class
mRNA
Alias
Translocase Of Outer Mitochondrial Membrane 34 HTOM34P TOM34 Outer Mitochondrial Membrane Translocase (34kD) Translocase Of Outer Membrane 34 KDa Subunit Mitochondrial Import Receptor Subunit TOM34 URCC3 HTom34
Location (GRCh38)
20:44942130-44960422
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Drug abuse diagnoses
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_006809.5
Sequence length
1973.0 nt
GC content
0.5236

Transcripts

ID Sequence Length GC content
NM_006809.5 NCBI
AAGGUGUGCCGCACCACACGGGGGAGGAAGGAAGGAGCUCCCAACUCGC… 1973 nt 0.5236
Summary

The protein encoded by this gene is involved in the import of precursor proteins into mitochondria. The encoded protein has a chaperone-like activity, binding the mature portion of unfolded proteins and aiding their import into mitochondria. This protein, which is found in the cytoplasm and sometimes associated with the outer mitochondrial membrane, has a weak ATPase activity and contains 6 TPR repeats. [provided by RefSeq, Jul 2008]

Forensic Context

A study in humans identified the TOMM34 as a single-gene blood biomarker, where machine-learning classifiers using differentially expressed genes could differentiate healthy controls from methamphetamine-dependent subjects with 87% accuracy [Breen et al. DOI:10.1038/tp.2016.67].