Basic Information

Symbol
TPCN1
RNA class
mRNA
Alias
Two Pore Segment Channel 1 TPC1 KIAA1169 Voltage-Dependent Calcium Channel Protein TPC1 Two Pore Calcium Channel Protein 1 Two Pore Channel Protein 1 FLJ20612 Two-Pore Channel 1, Homolog
Location (GRCh38)
12:113221050-113298589
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_017901.6
Sequence length
5248.0 nt
GC content
0.5747

Transcripts

ID Sequence Length GC content
NM_001143819.3 NCBI
GAGCUGGCGCAGCUGCCCUGGUGGCAGUGGCUGAAGUGGCGGCGGCUUC… 5341 nt 0.5739
NM_001301214.2 NCBI
CCCUUUCCUCCUUUGGCUUAAGCCUUUGGCAGGACAGAUUUUGGGCUGG… 4949 nt 0.5684
NM_001351346.2 NCBI
GAGCUGGCGCAGCUGCCCUGGUGGCAGUGGCUGAAGUGGCGGCGGCUUC… 5509 nt 0.5760
NM_001351347.1 NCBI
ACAUUUGCCCAGGGCUCUGCUUGGGUUUGGAGCCUUUACUAACGUGUGU… 5224 nt 0.5658
NM_017901.6 NCBI
GAGCUGGCGCAGCUGCCCUGGUGGCAGUGGCUGAAGUGGCGGCGGCUUC… 5248 nt 0.5747
Summary

Voltage-gated Ca(2+) and Na+ channels have 4 homologous domains, each containing 6 transmembrane segments, S1 to S6. TPCN1 is similar to these channels, but it has only 2 domains containing S1 to S6 (Ishibashi et al., 2000 [PubMed 10753632]).[supplied by OMIM, Mar 2008]

Forensic Context

No relevant information is available at the moment.