Basic Information

Symbol
TPPP
RNA class
mRNA
Alias
Tubulin Polymerization Promoting Protein TPPP/P25 TPPP1 P25alpha P25 Tubulin Polymerization-Promoting Protein Brain Specific Protein P25 Alpha 25 KDa Brain-Specific Protein P25-Alpha P24 Glycogen Synthase Kinase 3 (GSK3) Inhibitor P24 EC 3.6.5.-
Location (GRCh38)
5:659862-693997
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_007030.3
Sequence length
5979.0 nt
GC content
0.5941

Transcripts

ID Sequence Length GC content
NM_007030.3 NCBI
AGAGCUCCGCUGAGCACCGGGUCGCGCGCGGCCGAGUCGCGGAGGCGCC… 5979 nt 0.5941
Summary

Enables several functions, including magnesium ion binding activity; microtubule nucleator activity; and protein homodimerization activity. Involved in several processes, including microtubule cytoskeleton organization; negative regulation of tubulin deacetylation; and positive regulation of protein polymerization. Located in several cellular components, including cytoskeleton; mitochondrion; and perinuclear region of cytoplasm. Is active in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2025]

Forensic Context

No relevant information is available at the moment.