Basic Information

Symbol
TPST1
RNA class
mRNA
Alias
Tyrosylprotein Sulfotransferase 1 TANGO13A Protein-Tyrosine Sulfotransferase 1 EC 2.8.2.20 TPST-1 Transport And Golgi Organization 13 Homolog A (Drosophila) Transport And Golgi Organization 13 Homolog A
Location (GRCh38)
7:66205289-66420549
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_003596.4
Sequence length
1981.0 nt
GC content
0.4664

Transcripts

ID Sequence Length GC content
NM_003596.4 NCBI
AGACGCUGCUGAGGCGGCUUCGGUUGCGGGUCGGAACGGCGCUGCUCUG… 1981 nt 0.4664
Summary

Enables protein homodimerization activity and protein-tyrosine sulfotransferase activity. Involved in post-translational protein modification. Located in Golgi membrane. Implicated in colorectal adenocarcinoma. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in humans demonstrated that the TPST1 was upregulated during long-term weight loss (0 to 12 months) in weight losers within subcutaneous adipose tissue [Bollepalli et al. DOI:10.1038/ijo.2017.245].