Tyrosylprotein Sulfotransferase 1
TANGO13A
Protein-Tyrosine Sulfotransferase 1
EC 2.8.2.20
TPST-1
Transport And Golgi Organization 13 Homolog A (Drosophila)
Transport And Golgi Organization 13 Homolog A
Enables protein homodimerization activity and protein-tyrosine sulfotransferase activity. Involved in post-translational protein modification. Located in Golgi membrane. Implicated in colorectal adenocarcinoma. [provided by Alliance of Genome Resources, Jul 2025]
Forensic Context
A study in humans demonstrated that the TPST1 was upregulated during long-term weight loss (0 to 12 months) in weight losers within subcutaneous adipose tissue [Bollepalli et al. DOI:10.1038/ijo.2017.245].