Basic Information

Symbol
TRAK2
RNA class
mRNA
Alias
Trafficking Kinesin Protein 2 KIAA0549 ALS2CR3 CALS-C GRIF-1 OIP98 MILT2 Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 3 Protein Amyotrophic Lateral Sclerosis 2 (Juvenile) Chromosome Region, Candidate 3 O-Linked N-Acetylglucosamine Transferase Interacting Protein 98 Gamma-Aminobutyric Acid(A) Receptor-Interacting Factor Trafficking Protein, Kinesin Binding 2 Trafficking Kinesin-Binding Protein 2 Milton Homolog 2 (Drosophila) Milton Homolog 2 GRIF1
Location (GRCh38)
2:201377207-201453449
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Postmortem interval inference
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_015049.3
Sequence length
6389.0 nt
GC content
0.4156

Transcripts

ID Sequence Length GC content
NM_015049.3 NCBI
GGCAGUGGGAGCAGCGGCAGCAGCUUCGGCUGCUGCUUUCAGGCUGCCG… 6389 nt 0.4156
Summary

Predicted to enable GABA receptor binding activity and myosin binding activity. Predicted to be involved in several processes, including mitochondrion distribution; protein O-linked glycosylation; and vesicle transport along microtubule. Predicted to be located in cytoplasm; nucleus; and plasma membrane. Predicted to be active in cytoplasmic vesicle; dendrite; and mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]

Forensic Context

A longitudinal mRNA expression analysis in human post-mortem blood samples identified the TRAK2 as a protein-coding gene with an up-regulated expression pattern after death, where it is involved in the establishment of mitochondrion localization [Antiga et al. DOI:10.1038/s41598-021-96095-z].