Basic Information

Symbol
TRAT1
RNA class
mRNA
Alias
T Cell Receptor Associated Transmembrane Adaptor 1 TCRIM TRIM HSPC062 T-Cell Receptor-Associated Transmembrane Adapter 1 Pp29/30 T Cell Receptor Interacting Molecule T-Cell Receptor-Interacting Molecule
Location (GRCh38)
3:108822770-108855005
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_016388.4
Sequence length
1831.0 nt
GC content
0.3463

Transcripts

ID Sequence Length GC content
NM_001317747.2 NCBI
GGCACAGAUAAAGAUAAGUUUUACUGUCAUGCUGCUUUUAACAUAACAG… 1720 nt 0.3395
NM_016388.4 NCBI
GGCACAGAUAAAGAUAAGUUUUACUGUCAUGCUGCUUUUAACAUAACAG… 1831 nt 0.3463
Summary

Predicted to enable transmembrane receptor protein tyrosine kinase adaptor activity. Acts upstream of or within negative regulation of receptor recycling; negative regulation of transport; and positive regulation of signal transduction. Located in centriolar satellite; mitotic spindle; and plasma membrane. Part of T cell receptor complex. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in mice demonstrated that hypothermia-induced death significantly altered the pulmonary transcriptome, identifying the TRAT1 as an upregulated RNA marker with a 2.883-fold increase, classifying it as a candidate forensic biomarker of hypothermia [Takamiya et al. DOI:10.1016/J.Legalmed.2020.101789].