Basic Information

Symbol
TRIM23
RNA class
mRNA
Alias
Tripartite Motif Containing 23 RNF46 ARD1 ARFD1 ADP-Ribosylation Factor Domain-Containing Protein 1 ADP-Ribosylation Factor Domain Protein 1, 64kDa RING-Type E3 Ubiquitin Transferase TRIM23 Tripartite Motif-Containing Protein 23 E3 Ubiquitin-Protein Ligase TRIM23 GTP-Binding Protein ARD-1 RING Finger Protein 46 Tripartite Motif Protein TRIM23 Tripartite Motif-Containing 23 ARF Domain Protein 1 EC 2.3.2.27
Location (GRCh38)
5:65589690-65625975
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001656.4
Sequence length
3863.0 nt
GC content
0.3603

Transcripts

ID Sequence Length GC content
NM_001656.4 NCBI
AACCCCGCCUCUCAGUUGAGGACUCUGAAGGCUGUUUCUGUGGCGCUUC… 3863 nt 0.3603
NM_033227.3 NCBI
AACCCCGCCUCUCAGUUGAGGACUCUGAAGGCUGUUUCUGUGGCGCUUC… 2378 nt 0.3995
NM_033228.3 NCBI
AACCCCGCCUCUCAGUUGAGGACUCUGAAGGCUGUUUCUGUGGCGCUUC… 2349 nt 0.3985
Summary

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described. [provided by RefSeq, Jul 2008]

Forensic Context

No relevant information is available at the moment.