Basic Information
Symbol
TRIM27
RNA class
mRNA
Alias
Tripartite Motif Containing 27
RNF76
Ret Finger Protein
RFP
Tripartite Motif-Containing Protein 27
Zinc Finger Protein RFP
RING Finger Protein 76
RING-Type E3 Ubiquitin Transferase TRIM27
Tripartite Motif Protein TRIM27
Tripartite Motif-Containing 27
RFP Transforming Protein
EC 2.3.2.27
Location (GRCh38)
6:28903002-28923988
Forensic tag(s)
-
MANE select
Transcript ID
NM_006510.5
Sequence length
2963.0 nt
GC content
0.5451
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| ACGCUGCCGCCGGCAUCCGCUCGGACGCGGCCACGUUGUCUUGCGCGCU… | 2963 nt | 0.5451 |
Summary
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein. [provided by RefSeq, Jul 2008]
Forensic Context
No relevant information is available at the moment.