Basic Information

Symbol
TRIM35
RNA class
mRNA
Alias
Tripartite Motif Containing 35 HLS5 KIAA1098 MAIR Hemopoietic Lineage Switch Protein 5 E3 Ubiquitin-Protein Ligase TRIM35 Tripartite Motif-Containing Protein 35 Tripartite Motif-Containing 35 EC 2.3.2.27
Location (GRCh38)
8:27284886-27311289
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Postmortem interval inference
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_171982.5
Sequence length
4183.0 nt
GC content
0.5219

Transcripts

ID Sequence Length GC content
NM_001304495.2 NCBI
GCAAAAGUUCCGGGCGCCCGAGCCGGCUGCUCGUGCCAUGGAGCGGAGU… 4064 nt 0.5197
NM_001362813.2 NCBI
GCAAAAGUUCCGGGCGCCCGAGCCGGCUGCUCGUGCCAUGGAGCGGAGU… 4160 nt 0.5219
NM_171982.5 NCBI
GCAAAAGUUCCGGGCGCCCGAGCCGGCUGCUCGUGCCAUGGAGCGGAGU… 4183 nt 0.5219
Summary

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified. [provided by RefSeq, Jul 2008]

Forensic Context

A study in human post-mortem blood samples demonstrated that the TRIM35 was included in a post-mortem interval (PMI) prediction model, where it exhibited a negative coefficient and was part of a down-regulated gene expression cluster [Antiga et al. DOI:10.1038/s41598-021-96095-z].