Basic Information

Symbol
TRIM41
RNA class
mRNA
Alias
Tripartite Motif Containing 41 RINCK RING-Finger Protein That Interacts With C Kinase RING Finger-Interacting Protein With C Kinase E3 Ubiquitin-Protein Ligase TRIM41 MGC1127 RING-Type E3 Ubiquitin Transferase TRIM41 Tripartite Motif-Containing Protein 41 Tripartite Motif-Containing 41 EC 2.3.2.27
Location (GRCh38)
5:181222499-181235808
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Forensic psychiatry evaluation
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_033549.5
Sequence length
3645.0 nt
GC content
0.6052

Transcripts

ID Sequence Length GC content
NM_033549.5 NCBI
GCUUCCGGCAUCGGCUGUGGGGAGUACCGGCUGCAGUCGGCUGUGCCGG… 3645 nt 0.6052
NM_201627.3 NCBI
GCUUCCGGCAUCGGCUGUGGGGAGUACCGGCUGCAGUCGGCUGUGCCGG… 2705 nt 0.6122
Summary

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM family is characterized by a signature motif composed of a RING finger, one or more B-box domains, and a coiled-coil region. This encoded protein may play a role in protein kinase C signaling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Forensic Context

A study in human postmortem dorsolateral prefrontal cortex demonstrated that the TRIM41 exhibits a complex expression pattern in major depressive disorder and suicide [Pantazatos et al. DOI:10.1038/mp.2016.130].